China (Mainland)
Premiumsupplier
High Quality 99%Min Purity Epalrestat CAS 82159-09-9 CAS NO.82159-09-9
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,MoneyGram
- Product Details
Keywords
- 82159-09-9
- C15H13NO3S2
- Epalrestat
Quick Details
- ProName: High Quality 99%Min Purity Epalrestat ...
- CasNo: 82159-09-9
- Molecular Formula: C15H13NO3S2
- Appearance: yellow to orange, crystals or crystall...
- Application: Epalrestat is an aldose reductase inhi...
- DeliveryTime: as customers request
- PackAge: 1-5KG/Tin or Bag,25KG/Drum, 200KG/Drum
- Port: any port in China
- ProductionCapacity: 1000 Metric Ton/Year
- Purity: >99%
- Storage: Cool Dry Place
- Transportation: by sea or by air
- LimitNum: 1 Kilogram
Superiority
| 1)Quick Response Within 12 hours; |
| 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. |
| 3) OEM/ODM Available; |
| 4) Reasonable & Competitive Price; |
| 5) Fast Delivery: Samples from stock; bulk products within 7 days; |
| 6) Professional Documents for Your Clearance; |
| 7) Economic Freight Save Your Cost; |
| 8) All your money be refund immediately if quality issue happens. |
Details
Describtion:
Epalrestat is the second aldose reductase inhibitor to be introduced worldwide and the first to be launched in Japan. The compound is indicated for the treatment of diabetic neuropathy. It is also being investigated for diabetic retinopathy and nephropathy.
Epalrestat is a non-competitive inhibitor of aldose reductase, which reversibly inhibits the conversion of glucose into aldose reductase of sorbitol in polyol metabolism related to the pathogenesis of diabetic complications. Significantly improve the patient's symptoms and neurological dysfunction, improve its motor nerve conduction speed and autonomic nerve function.
Usage:
An aldose reductase inhibitor. It is used in treatment of diabetic neuropathy.
| Items | Specifications | Results | |||||
| Appearance | yellow to orange, crystals or crystalline powder, discoloration and decomposition under light | Complies | |||||
| Solubility | soluble in N, N-dimethylformamide,slightly soluble in methanol and in ethanol (99.5), and practically insoluble in water. | Complies | |||||
| Melting Point | 222~227℃ | 222.5~225.0℃ | |||||
| Identification | UV complies | Complies | |||||
| IR complies | Complies | ||||||
| Related substance | Single impurity | ≤0.20% | 0.04% | ||||
| Total impurities | ≤1.0% | 0.06% | |||||
| Residual solvent | Alcohol | ≤0.5% | 0.06% | ||||
| Tetrahydrofuran | ≤0.072% | 0.04% | |||||
| Acetic acid | ≤0.5% | No detected | |||||
| Loss on drying | ≤0.2% | 0.04% | |||||
| Residue on ignition | ≤0.1% | 0.00% | |||||
| Heavy metals | ≤10ppm | Complies | |||||
| Particle size | D50: 8~10μm | 9.4μm | |||||
| D90: 17~23μm | 19.8μm | ||||||
| Assay on dried | 98.0%~101.0% | 100.50% | |||||
| Conclusion | Complies with the requirement of JP17 | ||||||
| Containers and storage | Containers—Tight containers | Storage—Light-resistant | |||||