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High Quality Lamivudine Powder Price CAS 134678-17-4 CAS NO.134678-17-4
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- Lamivudine
- 134678-17-4
- C8H11N3O3S
Quick Details
- ProName: High Quality Lamivudine Powder Price C...
- CasNo: 134678-17-4
- Molecular Formula: C8H11N3O3S
- Appearance: white powder
- Application: Immune & Anti-Fatigue
- DeliveryTime: as customers request
- PackAge: 1-5KG/Tin or Bag,25KG/Drum, 200KG/Drum
- Port: any port in China
- ProductionCapacity: 1000 Metric Ton/Year
- Purity: >99%
- Storage: Cool Dry Place
- Transportation: by sea or by air
- LimitNum: 1 Kilogram
Superiority
| 1)Quick Response Within 12 hours; |
| 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. |
| 3) OEM/ODM Available; |
| 4) Reasonable & Competitive Price; |
| 5) Fast Delivery: Samples from stock; bulk products within 7 days; |
| 6) Professional Documents for Your Clearance; |
| 7) Economic Freight Save Your Cost; |
| 8) All your money be refund immediately if quality issue happens. |
Details
Description
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor. Lamivudine has been used for treatment of chronic hepatitis B at a lower dose than for treatment of HIV. It improves theseroconversion of e-antigen positive hepatitis B and also improves histology staging of the liver. Long term use of lamivudine unfortunately leads to emergence of a resistant hepatitis B virus (YMDD) mutant. Despite this, lamivudine is still used widely as it is well tolerated.
Specification
| Items Tested | Specification | Results |
| Description | A white or off-white crystall powder | A white crystall powder |
| Solubility | Soluble in water. | Meets the requirements |
| Identification | ||
| a). By HPLC | The retention time of the major peak of the sample solution corresponds to that of the system suitability solution, as obtained in the test for limit of Lamivudine Enantiomer. | Meets the requirements |
| b). By IR | The infrared absorption of sample should exhibit maxima only at the same wavelengths as that of standard. | Meets the requirements |
| Water by KF | Not more than 0.2% | 0.07% |
| Melting range | Between 174.0ºC and 178.0ºC | 176.8ºC~177.8ºC |
| Absorptivity | Not more than 0.0015 | 0.0002 |
| Related substances | ||
| Lamivudine-carboxylic acid | Not more than 0.3% | 0.05% |
| Lamivudine diastereomer | Not more than 0.2% | 0.06% |
| Salicylic acid | Not more than 0.1% | Not detected |
| Any other individual impurity | Not more than 0.1% | 0.03% |
| Total impurities | Not more than 0.6% | 0.15% |
| Limit of Lamivudine Enantiomer | Not more than 0.3% | 0.01% |
| Assay | Between 98.0% and 102.0% on anhydrous and solvent-free basis. | 100% |
| Limit of residual solvents | ||
| Alcohol | Not more than 0.2% | Not detected |
| Isopropyl acetate | Not more than 0.2% | Not detected |
| Methanol | Not more than 0.1% | Not detected |
| Triethylamine | Not more than 0.1% | Not detected |
| Isopropyl alcohol* | Not more than 0.5% | 0.16% |
| Ethyl acetate * | Not more than 0.5% | Not detected |
| Toluene* | Not more than 0.089% | Not detected |
| Dichloromethane* | Not more than 0.06% | Not detected |
| Normal hexane * | Not more than 0.029% | Not detected |
| DMF* | Not more than 0.088% | Not detected |
| Total residual solvents | Not more than 0.3% | 0.16% |
| Remark:*The solvents are used in the manufacturing process of lamivudine besides those listed in usp41. | ||