3, 3-Methylenebisindole Dim CAS 1968-05-4 Diindolylmethane CAS NO.1968-05-4

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Basic information

Diindolylmethane is formed in the body from plant substances contained in "cruciferous" vegetables such as cabbage, Brussels sprouts, cauliflower, and broccoli. Scientists think these vegetables may help to protect the body against cancer because they contain diindolylmethane and a related chemical called indole-3 carbinol. Diindolylmethane is used for preventing breast, uterine, and colorectal cancer. It is also used to prevent an enlarged prostate (benign prostatic hypertrophy, BPH) and treat premenstrual syndrome (PMS). 

Function of diindolylmethane
Abnormal growth of cells of the cervix (cervical dysplasia). 
Prostatecancer. 
Preventing breast cancer.
Preventing uterine cancer.
Preventing colon cancer.
Preventing prostate enlargement (benign prostatic
 hypertrophy, BPH).
Treating premenstrual syndrome (PMS).

Application of diindolylmethanediindolylmethane
A natural phytochemical found in cruciferous plants, an acid catalyzed reaction product,
indole-3-methanol; It has the function of anti-tumor agent. Under the condition of relatively high concentration, this derivative can not only directly accelerate the apoptosis of human cancer cells, but also sensitize TRAIL to induce the apoptosis of human cancer cells. DIM induces a G1 cell ring inhibition in human breast cancer MCF-7 cells, through mechanism, including expression; DIM is a potent mitochondrial H+-ATPase inhibitor. As a new plant growth promoter, DIM and its derivatives have been used in eco-friendly systematic research

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