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Home > Products >  CAS 103-90-2 Panadol Acetaminophen Paracetamol

CAS 103-90-2 Panadol Acetaminophen Paracetamol CAS NO.103-90-2

  • Min.Order: 1 Kilogram
  • Payment Terms: T/T,
  • Product Details

Keywords

  • 103-90-2
  • Paracetamol
  • C8H9NO2

Quick Details

  • ProName: CAS 103-90-2 Panadol Acetaminophen Par...
  • CasNo: 103-90-2
  • Molecular Formula: C8H9NO2
  • Appearance: White free flowing granules
  • Application: .Paracetamol is the most commonly used...
  • DeliveryTime: as customers request
  • PackAge: 1-5KG/Tin or Bag,25KG/Drum, 200KG/Drum
  • Port: any port in China
  • ProductionCapacity: 1000 Kilogram/Year
  • Purity: >99%
  • Storage: Cool Dry Place
  • Transportation: BY SEA OR BY AIR
  • LimitNum: 1 Kilogram

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Details

Paracetamol:
powder nutritional supplemen Mainly used for amino acid infusion,due to special wettability, also used in cold cream,osmetics. Serine constitute the human body of several kinds of essential amino acid of protein a, for the construction of protein has a very important role. 
Paracetamol(Acetaminophen):

The antipyretic and analgesic acetaminophen, this product is a metabolite of phenacetin, regulates central prostaglandin synthase by inhibiting hypothalamic body temperature. Reduce the synthesis and release of prostaglandin PGE1, bradykinin and histamine. PGE1 mainly acts on the nerve center. Its decrease will lead to a decrease in the central body temperature setting point, and the body surface temperature sensor will feel relatively hot, and then through nerve regulation, it will cause peripheral blood vessels to dilate and sweat to achieve antipyretic effect, which inhibits the central nervous system. The effect of prostaglandin synthesis is similar to that of aspirin, but its anti-inflammatory effect is weak. No effect on platelets and coagulation mechanism. Indications: Used for cold and fever, joint pain, neuralgia, migraine, cancer pain and postoperative pain relief. This product can also be used for patients who are allergic to aspirin, intolerant or not suitable for aspirin (chickenpox, hemophilia and other bleeding disorders, etc.).

Function

1.Paracetamol is the most commonly used non-anti-inflammatory antipyretic analgesics, antipyretic effect similar analgesic effect is weak, no anti-inflammatory anti-rheumatic effects, acetanilide drugs is the best varieties. Particularly suitable for patients who can not use carboxylic acids. For cold, toothache embolism. Acetaminophen is also an intermediate for organic synthesis, hydrogen peroxide stabilizer, and photographic chemicals.
2.Paracetamol for antipyretic, analgesic, anti-rheumatic drugs
3.Paracetamol for organic synthesis intermediates, hydrogen peroxide stabilizer, photographic chemicals, non-anti-inflammatory antipyretic analgesics.

Product Name Paracetamol  
Shel Life 3 years  
Tests Specification Results
Appearance White or almost free flowing granules White free flowing granules
Identification

A:The IR spectra of the sample compares to that of the standard

Positive
B:The retention times of the major peaks from the sample solution correspond to those from the standard solution, as obtained in the Assay Positive
Water 0.6%-1.5% 0.72%
Bulk density 0.40-0.60 g/ml 0.48g/ml
Tapped density 0.50-0.69g/ml 0.59g/ml
Organic impurities Related compound B N- (4-HydroxyphenyI) propanamide not more than 0.05% 0.02%
Related compound C N- (2-HydroxyphenyI)  acetamide not more than 0.05% 0.004%
Related compound D (N-Phenylacetamide) not more than 0.05% 0.0003%
Related compound J N-(4-ChlorophenyI) acetamide (p-chloroacetanilide) not more than 0.001% Not detected
Individual unspecified impurity not more than 0.05% 0.007%
Total impurities not more than 0.1% 0.04%
Free p-aminophenol Not more than 0.005% 0.0003%
Particle size(sieve) Retained on US No.60: NMT 25.0% 22.8%
Retained on US No.100: NMT 70.0% 57.5%
Retained on US No.200: NMT 95.0% 84.3%
Retained on US No.325: NLT 80.0% 95.6%
Residue on ignition Not more than 0.14% 0.07%
Heavy metals Not more than 0.001% Less than 0.001%
Assay(anhydrous basis) 87.5%~92.5% 90.0%
Microbial limits Total aerobic microbial count not more than 1000cfu/g Less than 10cfu/g
Total combined molds and yeasts count not more than 100cfu/g Less than 10cfu/g
Escherichia coli should be absent Not detected

Salmonella should be abent

Not detected
Residual solvents Not applicable as no solvents are used in the manufacturing process of PARACETAMOL ( ACETAMINOPHEN) DC 90%
CONCLUSION:   The product conforms to the above specifications

 

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